For large scale cultivation, Haematococcus is cultivated in a two-stage process – green stage and red stage. In the green stage, vegetative cells are produced under near-optimal growth conditions with careful control of pH, temperature and nutrient levels. Regulation of pH can be controlled automatically with metered solenoids and carbon dioxide fed on demand. Temperature control can also be maintained automatically with metered solenoids and thermocouples. The cultivation is carried out in photobioreactors or open raceway ponds or a combination of both. After a sufficient volume of vegetative cells is produced, the culture is moved to second cultivation stage.